Terlipressin Acetate API

Physicochemical Properties

CAS No.: 14636-12-5

Purity: ≥99% (HPLC)
Molecular Formula: C₅₂H₇₄N₁₄O₁₅S₂·xC₂H₄O₂（x=3-5）Theoretical Molecular Weight: 1227.4 Da (free base)
Appearance: White to off-white lyophilized powder
Storage Conditions: -20°C±5°C (dry, protected from light)
Sequence: Gly-Gly-Gly-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH₂(N-terminal tri-glycine extended vasopressin analog)
Solubility: DMSO (Slightly), Methanol (Slightly)

Indications

1. For acute hemostasis in cirrhosis-related esophageal-gastric variceal bleeding.
2. For hepatorenal syndrome (HRS).

Structural Formula