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Leuprorelin API

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Product Introduction


Physicochemical Properties

CAS No.: 53714-56-0

Purity: ≥99% (HPLC)

Appearance: White or off-white lyophilized powder 

Molecular Formula: C59H84N16O12

Molecular Weight: 1209.4

Density: 1.44 ± 0.1 g/cm³ (Predicted)

Storage Conditions: -20°C±5°C (dry, protected from light)

Sequence: 

pGlu-His-Trp-Ser-Tyr-D-Leu-Leu-Arg-Pro-NHEt

Solubility: Slightly soluble in DMSO, methanol, and water

Water Solubility: 1 mg/mL

Stability: Hygroscopic

Indications

Oncology Indications: 

- Advanced hormone-dependent prostate cancer; hormone receptor-positive breast cancer (premenopausal/perimenopausal women); endometriosis; uterine fibroids (preoperative volume reduction)

Non-Oncology Indications: 

- Central precocious puberty (CPP) (suppresses premature puberty); assisted reproductive technology (ART) (pituitary down-regulation before controlled ovarian hyperstimulation)

Structural Formula

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